lncRNA GCAT1 is involved in premature ovarian insufficiency by regulating p27 translation in GCs via competitive binding to PTBP1
نویسندگان
چکیده
منابع مشابه
risk taking in english to persian translation process by novice iranian translators
این پژوهش به بررسی ریسک پذیری مترجمان تازه کار در طی فرآیند ترجمه از زبان انگلیسی به فارسی می پردازد. پژوهش درباره مترجمان به عنوان اولین خواننده متن مبدا از اهمیت به سزایی برخوردار است. مترجمان تازه کار (و حرفه ای) در طی فرآیند ترجمه با مشکلات متعددی روبرو می شوند که باعث عدم اطمینان آنها از متن ترجمه شده می شود. با توجه به اینکه عدم اطمینان به انجام ریسک منتهی می شود، هدف این پژوهش بررسی کیفی...
Role of microRNAs in premature ovarian insufficiency
Premature ovarian insufficiency (POI) is a typical disorder of amenorrhea lasting for a minimum of 4 months. The typical characteristics comprised of declined estrogen and raised serum concentrations of follicle-stimulating hormone (FSH) in women <40-year-old, primarily originating from iatrogenic factors, karyotypic abnormalities, and genetic factors. However, the etiology of POI remains unkno...
متن کاملA mouse model of premature ovarian insufficiency induced by tripterygium glycoside via subcutaneous injection.
Premature ovarian insufficiency (POI) is a main cause of infertility and affects nearly 1% women under 40 years old. This study was aimed to utilize the side effects of tripterygium glycoside (TG) to induce a mouse model of POI. 48 female KM mice were divided into four groups: control, oral, intraperitoneal injection and subcutaneous injection group. The mice in last three groups were treated w...
متن کاملPossible Role of Autoimmunity in Patients with Premature Ovarian Insufficiency
BACKGROUND To evaluate the involvement of immune abnormality in patients with idiopathic premature ovarian insufficiency (POI). In addition to the known etiology, autoimmune disorders may be a pathologic mechanism for POI. MATERIALS AND METHODS Our study was a prospective controlled trial. Twenty women with POI, reasons other than autoimmune excluded, were enrolled in this study. The control ...
متن کاملLncRNA NEAT1 contributes to paclitaxel resistance of ovarian cancer cells by regulating ZEB1 expression via miR-194
Background Chemoresistance is one of the major obstacles for cancer therapy in the clinic. Nuclear paraspeckle assembly transcript 1 (NEAT1) has been reported as an oncogene in most malignancies such as lung cancer, esophageal cancer, and gastric cancer. This study is designed to investigate the function of NEAT1 in paclitaxel (PTX) resistance of ovarian cancer and its potential molecular mecha...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Molecular Therapy - Nucleic Acids
سال: 2021
ISSN: 2162-2531
DOI: 10.1016/j.omtn.2020.10.041